Table 1. Summary of mutation type by patient.

	Patient 1	Patient 2	Patient 3	Patient 4	Patient 5	Patient 6
Nonsynonymous coding	20	30	31	44	101	34
Synonymous coding	13	12	0	0	0	0
Insertions/deletions	1	4	0	6	0	2
Stop gained	0	3	3	2	6	2
Start gained	0	1	0	0	0	0
Codon insertion	0	1	0	0	0	1
Codon deletion	0	0	0	0	0	1
Splice site donor	0	0	1	0	1	2
Splice site acceptor	0	0	0	0	4	0
Total	34	51	35	52	112	42