Figure 3. A 24-AUY922 reduces Mf output from female worms.

Graph shows the mean (± SD) Mf output from groups of six female B. pahangi worms exposed to 250 nM, 25 nM or 10 nM NVP-AUY922 for a period of 24 h only (time 0). Worms were washed free of drug and cultures continued in medium alone for a further 24 h or 48 h and Mf output quantified. P<0.05 for 250 nM and 25 nM compared to control at all time points; for 10 nM drug, P<0.05 for 48 h only. Results shown are representative of two experiments.