Figure 2. Parasite burden of the lesions before treatment (1^st biopsy) and after wound closure (2^nd biopsy).

▪ Patients, who received EC plus MWT with DAC N-055 (group I); ▪ patients, who received EC plus MWT without DAC N-055 (group II). Each symbol (▪, ▪) represents one biopsy; horizontal lines mark the mean value of each group. After wound closure (2^nd biopsy) 42 out of 59 biopsies in group I and 37 out of 54 in group II were Leishmania-negative (not shown). Level of significance was estimated using Student's t-test (*, p<0.05).