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. 2014 Feb 13;9(2):e86945. doi: 10.1371/journal.pone.0086945

Figure 2. Increased PAR-2 dependent calcium response in asthmatic bronchial smooth muscle cells.

Figure 2

Representative intracellular calcium responses following stimulation by 10−4 M SLIGKV-NH2 for 30 sec are presented in bronchial smooth muscle cells from asthmatic (black line) or control subjects (grey line) (A). Basal calcium concentration (Basal [Ca2+]i, B), relative calcium response ([Ca2+]i peak, C) and area under the curve (AUC [Ca2+]i, D) were assessed from cell response to 10−4 M SLIGKV-NH2. Bronchial smooth muscle cells were obtained from asthmatic (black bars, n = 3) and control subjects (white bars, n = 3). Results are expressed as mean ± SEM from a range of 14 to 41 cells per patient. *P<0.05 using Mann & Whitney test.