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. 2014 Feb 13;9(2):e88360. doi: 10.1371/journal.pone.0088360

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© 2014 Janssen et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A: Body weight was significantly reduced in presence of Prednisolone. B: EDL weight showed a similar pattern to body weight. C: Body weight and EDL weight show a close correlation. D: Total EDL force/BW shows a similar ratio in all groups, with a non-significant (P = 0.09) trend to be lower in untreated mdx mice. C57BL/10, n = 4–8; U: untreated mdx mice, n = 6, P: Prednisolone treated mdx mice, n = 10, LS: Lisinopril-Spironolactone treated mdx mice, n = 10; LSP, Lisinopril-Spironolactone-Prednisolone treated mdx mice n = 6; TS: Losartan-Spironolactone treated mdx mice, n = 11; TSP: Losartan-Spironolactone-Prednisolone treated mdx mice, n = 8. * indicates a significantly lower value compared to the equivalent primary treatment without Prednisolone, P<0.05.