Skip to main content
. 2014 Feb 13;9(2):e88360. doi: 10.1371/journal.pone.0088360

Figure 8. Collagen I immunostaining of hearts from Prednisolone treated mice confirms the presence of Collagen scarring replacing cardiac muscle.

Figure 8

The damage present in hearts from P treated mice has progressed to collagen-containing fibrotic scarring in 20 week-old mice. LS shows no negative effects on mdx hearts. C: C57BL/10; U: untreated mdx mice, P: Prednisolone treated mdx mice, LS: Lisinopril-Spironolactone treated mdx mice; LSP, Lisinopril-Spironolactone-Prednisolone treated mdx mice; TS: Losartan-Spironolactone treated mdx mice; TSP: Losartan-Spironolactone-Prednisolone treated mdx mice. Bar = 100 µm.