Table 2.

Cancer specific and overall survival comparing different treatment strategies in all patients

		Cancer specific survival		Overall survival
		PS-adjusted HR (95% CI)	p-value	PS-adjusted HR (95% CI)	p-value
Overall	Unimodal (ref. group) vs. bimodal therapy	0.67 (0.60–0.74)	<0.001	0.57 (0.52–0.62)	<0.001
	Surgery only (ref. group) vs. EBRT only	1.19 (1.05–1.35)	0.008	1.25 (1.11–1.41)	<0.001
	Surgery only vs. EBRT only, first 7 months	0.85 (0.70–1.03)	0.09	0.70 (0.58–0.85)	<0.001
	Surgery only vs. EBRT only, 8 to 60 months	1.33 (1.13–1.56)	<0.001	1.47 (1.27–1.71)	<0.001
	Preoperative (ref. group) vs. postoperative EBRT	1.03 (0.87–1.22)	0.74	1.14 (0.97–1.33)	0.10

Estimations for CSS were performed using competing-risks regression model while for OS, cox proportional hazard models were performed. For the calculation of the propensity score (PS), the following covariates were used: gender, age (≤65 years, >65 years), race, ethnicity, marital status, tumor grade, tumor location, tumor T-stage, histology, and year (5 consecutive groups). vs.=versus, EBRT = External beam radiotherapy, ref.=reference, HR=Hazard ratio, CI=95% confidence interval