Table 3.

TIME-DEPENDENT PREDICTORS OF DEPRESSION SEVERITY IN 138 OLDER ADULTS WITH MAJOR DEPRESSION AND SEVERE COPD RANDOMLY ASSIGNED TO PID-C OR USUAL CARE

Variables	F	df	p
Depression Severity (HAM-D 17)
Model 1: Adherence to Antidepressants*
Treatment1	0.50	1, 235	0.58
Time2	0.58	1, 156	0.45
Treatment1 x time2	1.01	1, 156	0.32
Adherence to Antidepressants	5.21	1, 236	0.023
Model 2: Dyspnea-Related Disability**
Treatment1	1.32	1, 132	0.253
Time2	0.02	1, 81.1	0.90
Treatment1 x Time2	0.05	1, 80.3	0.83
Dyspnea Related Disability	4.64	1, 146	0.033

¹Treatment: Personalized Intervention for Depression and COPD (PID-C) vs. Usual Care

²Time in days

^*The model evaluates the relationship of adherence at 6 and 22 weeks after discharge to HAM-D at 14 and 28 weeks respectively

^**The model evaluates the relationship of PFSDQ-M at discharge and 14 weeks to HAM-D at 14 and 28 weeks respectively