Table 1. The list of genes in clusters obtained using HCNE based analysis in the GRB model.
| Gene Name | Cluster ID | Homology-based subfamily | Mechanism of action |
| NR1D1 | 1 | I | NHR |
| RARA | 1 | I | NHR |
| THRA | 1 | I | NHR |
| NR4A3 | 1 | IV | NOR |
| NR6A1 | 1 | VI | NOR |
| NR1D2 | 1 | I | NHR |
| RARB | 1 | I | NHR |
| THRB | 1 | I | NHR |
| RARG | 1 | I | NHR |
| HNF4G | 1 | II | NHR |
| NR0B1 | 1 | 0 | NOR |
| NR2E1 | 1 | II | NOR |
| NR5A1 | 1 | V | NHR |
| RORA | 1 | I | NHR |
| RORB | 1 | I | NHR |
| NR0B2 | 1 | 0 | NOR |
| NR4A2 | 1 | IV | NOR |
| ESRRG | 1 | III | NOR |
| NR5A2 | 1 | V | NHR |
| NR2F1 | 1 | II | NOR |
| NR2F2 | 1 | II | NOR |
| NR4A1 | 1 | IV | NOR |
| RXRG | 1 | II | NHR |
| PPARG | 1 | I | NHR |
| ESRRB | 1 | III | NOR |
| NR1H3 | 2 | I | NHR |
| AR | 2 | III | NHR |
| NR2C1 | 2 | II | NOR |
| RORC | 2 | I | NHR |
| NR2E3 | 2 | II | NOR |
| NR1I2 | 2 | I | NHR |
| NR1H4 | 2 | I | NHR |
| ESR1 | 2 | III | NHR |
| ESR2 | 2 | III | NHR |
| NR2C2 | 2 | II | NOR |
| NR1H2 | 2 | I | NHR |
| PGR | 2 | III | NHR |
| RXRA | 2 | II | NHR |
| NR3C1 | 2 | III | NHR |
| NR3C2 | 2 | III | NHR |
| PPARD | 2 | I | NHR |
| VDR | 2 | I | NHR |
| NR1I3 | 2 | I | NHR |
| RXRB | 2 | II | NHR |
| NR2F6 | 2 | II | NOR |
| PPARA | 2 | I | NHR |
| HNF4A | 2 | II | NHR |
| ESRRA | 2 | III | NOR |
The homology-based classification is into seven categories: (I) Thyroid Hormone Receptor-like, (II) Retinoid X Receptor-like, (III) Estrogen Receptor-like, (IV) Nerve Growth Factor IB-like, (V) Steroidogenic Factor-like, (VI) Germ Cell Nuclear Factor-like, and (0) Miscellaneous. The functional classification is into nuclear hormone receptors (NHR) and nuclear orphan receptors (NOR).