Figure 7. Effect of inhibition of the NF-κB pathway on the induction of endothelial adhesion molecule expression by SCA PLTs.

The expressions of (A) ICAM-1 (CD54) and (B) E-selectin (CD62E) were determined by flow cytometry on HUVEC (1×10⁶ cells/well) following co-culture in direct contact with CON PLTs (N≥13) or SCA PLTs (1×10⁸ PLTs/well; N≥14) in the presence or absence of BAY 11-7082 (20 µM; 4 h, 37°C, 5% CO₂). *, P<0.05; **, P<0.01, compared to basal (N≥12).