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. 2014 Feb 13;9(2):e89011. doi: 10.1371/journal.pone.0089011

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© 2014 Saeki et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(a) Schematic model of the shadow imaging. (b) Simulated profile of light intensity received at the sensor surface below the microcavity array. The black line indicates a profile with no cells present in the closely aligned microcavities. The red line indicates a profile with a single cell trapped on one of the closely aligned microcavities. I₀ was defined as 1.0. The light through the trapped cell was assumed to be attenuated by 100%.