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. 2013 Aug 27;2:407. doi: 10.1186/2193-1801-2-407

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© Khatun et al.; licensee Springer. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Representative photographs showing HD-induced histological changes in DG region of hippocampus. HD induced shrinkage and scattering of neuronal cells with gradual decrease in number during early period (Figs. HD, 1–6 H; arrows) as compare to their respective CD groups (Figs. CD, 1–6 H). CD induced disruption of histoarchitecture of DG region and increased necrotic changes after 6 h (CD, 12 H). Enlarge view of morphological changes in neuronal cells of the same figure (inset). Scale bar = 50 μM.