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. 2013 Aug 27;2:407. doi: 10.1186/2193-1801-2-407

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© Khatun et al.; licensee Springer. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Representative photographs showing HD-induced p53 activity in neuronal cells of the DG region. (A) HD increased number of p53 positive cells in a time-dependent manner (Figs. HD, 1–6 H) during initial period (1–6 h) as compared to their respective CD groups (Figs. CD, 1–6 H). Enlarge view of p53 positive neuronal cells of the same figure (inset). Scale bar = 50 μM. (B) Quantitative analysis of p53 positive neuronal cells in DG region. Data are mean ± SEM of three independent experiments and analyzed by One-Way ANOVA followed by Tukey test. “*” Denote significantly different at p < 0.05 level. Blue line denote HD, red line denote CD.