. Author manuscript; available in PMC: 2015 Feb 1.

Published in final edited form as: Osteoarthritis Cartilage. 2013 Dec 5;22(2):275–283. doi: 10.1016/j.joca.2013.11.013

Table I.

Histomorphometry results.

		Calcium deposition	Tidemark integrity		Glycosaminoglycan thickness
		Calcium deposition	Variance of first derivate (μm²)	Mean peak amplitude (μm)	UFC (μm)	CFC (μm)
LA	Healthy	1.03 (0.45, 1.60)^*	5.62 (0.16, 11.08)	1.02 (.74, 1.30)	239.68 (187.24, 292.11)	209.21 (164.05, 254.37)^*
LA	OA	2.94 (2.08, 3.80)	14.74 (−2.54, 32.01)	1.63 (0.89, 2.37)	577.26 (211.56, 942.96)	371.91 (142.06, 601.75)
LP	Healthy	0.97 (0.38, 1.57)	8.95 (3.09, 14.80)	1.33 (0.95, 1.72)	745.72 (240.95, 1250.49)	182.89 (153.57, 212.21)
LP	OA	2.50 (1.11, 3.89)	20.74 (−4.86, 46.34)	1.85 (0.64, 3.05)	809.65 (329.27, 1290.04)	264.04 (184.89, 343.20)
MA	Healthy	1.06 (0.38, 1.73)^*	2.59 (0.94, 4.23)^*	0.88 (0.69, 1.08)^*	265.83 (−15.70, 547.36)	120.95 (65.69, 176.69)^*
MA	OA	2.63 (1.70, 3.55)	17.15 (−1.02, 35.31)	1.85 (0.79, 2.91)	1054.15 (298.72, 1809.57)	226.41 (156.78, 296.03)
MP	Healthy	2.06 (1.27, 2.84)	4.36 (1.77, 6.94)	1.20 (0.95, 1.45)	450.25 (32.88, 867.61)	257.76 (196.19, 319.33)^*
MP	OA	1.63 (0.16, 3.09)	75.09 (−49.00, 199.17)	3.19 (0.17, 6.21)	658.87 (338.40, 979.33)	591.12 (253.48, 928.76)

There was a significant amount of calcium deposition in both anterior entheses. The TM was significantly less organized in the arthritic MA enthesis. GAG thickness was significantly greater in arthritic LA, MA, and MP entheses.

– represents significant difference (P < 0.05) between healthy and OA tissue for a specific enthesis. Mean (95% CI lower limit, upper limit) (N = 8 healthy knees, N = 7 OA knees)