Table 1.
Toxicology of BENC-511 in nude mice: hematology analysis
| Treatment | WBC (10 9 /L) | RBC (10 12 /L) | HGB (g/L) | PLT (10 9 /L) |
|---|---|---|---|---|
| Control |
1.81 ± 0.65 |
7.54 ± 1.37 |
110.00 ± 18.80 |
511.92 ± 134.68 |
| BENC-511 |
1.70 ± 0.50 |
8.18 ± 1.97 |
123.80 ± 29.78 |
530.50 ± 112.82 |
| P | 0.89 | 0.68 | 0.47 | 0.58 |
Data represent mean ± SD of 6 nude in each group. Female nude mice (n = 6 mice per group) were treated with BENC-511 at 50 mg/kg body weight or vehicle for 20 days. Blood samples were collected in tubes containing EDTA as anticoagulant and subject to hematological analysis. WBC: White blood cell; RBC: Red blood cell; PLT: Platelets; HGB: haemoglobin.