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Central administration of recombinant CTRP4 alters food intake and body weight in lean and obese mice. Shown are food intake (A), body weight (B), and physical activity (C) of lean chow-fed mice (n = 5) injected centrally with recombinant CTRP4. Also shown are food intake (D), body weight (E), and physical activity (F) of obese HFD-fed mice (n = 6) injected centrally with recombinant CTRP4. Observations were made over the course of 3 days. *, p < 0.05.
