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Effect of rapamycin on the expression of myosin light chain-2 and myosin heavy chain α6 proteins in the heart. A, representative immunoblots of MLC-2, MHCα6, and GAPDH in hearts of C57 and db/db mice following 28 days of rapamycin treatment. B and C, densitometric analysis of the ratios of MLC-2 to GAPDH (B) and MHCα6 to GAPDH (C).
