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. 2013 Dec 23;289(7):4173–4179. doi: 10.1074/jbc.M113.533034

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FIGURE 4. — Nlrx1^−/− mice suffer worse outcomes in response to encephalitogenic T cells. A, clinical scores of WT and Nlrx1^−/− mice after transfer of encephalitogenic T cells. n = 9 mice/group. B, flow cytometric analysis of peripheral immune cell (CD45^high) infiltration into spinal cord tissue at 16 dpi. Left panel, contour map depicting the selection of the CD45^high cell population. Right panel, total number of CD45^high cells per spinal cord. FS, forward scatter (10³). n = 5 mice/group. C, analysis of T cell infiltrates into spinal cord tissue after encephalitogenic T cell transfer. Left panel, contour map depicting the selection of CD45^high CD3⁺ cells. Right panel, total numbers of CD45^high CD3⁺ cells in WT and Nlrx1^−/− mice. n = 9 mice/group. Error bars represent mean ± S.E. *, p < 0.05.