FIGURE 8.

Location of the residues involved in binding to MDA-BSA in the crystal structure of FH19–20. The structure of FH19–20 published previously (PDB code 2G7I) was used to visualize the location of the residues observed to be involved in MDA-BSA binding (Fig. 3A). A mesh representation of FH19–20 is shown, with the residues important in the interaction with MDA-BSA marked with dark gray. Distances between the tips of the side chains are indicated in ångströms next to the dashed lines. A modeled structure of an MDHDC adduct is shown on the right for size comparison.