Figure 2.

Relative complement mapping consistency of GNUMAP-bs with HEP methylation profiles of human chromosome 22. Venn diagrams between GNUMAP-bs and (a) Novoalign, (b) BSMAP, and (c) Bismark showing both the number of covered/uncovered CG sites and the concordance (in parenthesis) of these sites with the HEP methylation profiles. The estimated levels of methylation in the additional CG sites covered by the probabilistic aligners but not by the other aligners are highly concordant with the HEP results.