Figure 2.

(a) Individual variability in Risky Decision-making Task (RDT) performance during adolescence (pre-SA). Each line represents performance of one rat in the RDT (n=42). Percent choice of the large, risky reward is shown on the y-axis; risk of footshock is shown on the x-axis. (b) Adolescent RDT performance in rats designated as ‘risk taking' and ‘risk averse', which then underwent cocaine SA (n=28). Note that this does not include the rats (n=14) characterized in adolescence that then underwent sucrose SA. (c) Adolescent risk taking predicts cocaine SA in adulthood. Over the course of the 5 days of acquisition of cocaine SA (x-axis), risk taking rats (closed circles) self-administered significantly more cocaine (y-axis) than risk averse rats (open circles).