Skip to main content
. 2013 Nov 20;39(4):1031–1038. doi: 10.1038/npp.2013.306

Figure 5.

Figure 5

Effect of the direct administration of ammonia and TBOA on striatal glutamate: artificial cerebrospinal fluid (aCSF), ammonia (200 μM), DL-threo-β-benzyloxyaspartic acid (TBOA; 500 μM) or the combination of ammonia and TBOA were reverse dialyzed and striatal glutamate was measured every 30 min using in vivo microdialysis. Ammonia significantly increases local striatal glutamate concentrations (*P<0.005) and this increase is blocked by TBOA pretreatment and co-administration (n=5–6 rats per group).