Table 4.

Adjusted^* Odds Ratio (and 95% confidence interval) from logistic^† and GEE^‡ regression models for quartiles of MDA-LDL-IC in relation to elevated internal carotid IMT and IMT progression

	6 Year ICA IMT†	12 Year ICA IMT†	IMT Progression Year 1 to 12†	Elevated ICA IMT‡
Model 1*
Lowest Quartile	1.00	1.00	1.00	1.00
Quartile 2	2.88 (1.29-6.40)	1.59 (0.69-3.64)	1.14 (0.49-2.64)	1.33 (0.66-2.60)
Quartile 3	1.58 (0.69-3.63)	1.50 (0.64-3.51)	1.62 (0.72-3.64)	1.29 (0.64-2.60)
Quartile 4	2.71 (1.28-5.76)	2.82 (1.26-6.31)	2.58 (1.18-5.64)	2.43 (1.26-4.68)
ROC AUC	0.744	0.802	0.772
Model 2*
Lowest Quartile	1.00	1.00	1.00	1.00
Quartile 2	2.55 (1.12-5.82)	1.42 (0.59-3.40)	1.00 (0.40-2.53)	0.89 (0.43-1.83)
Quartile 3	1.31 (0.58-2.97)	1.24 (0.52-2.99)	1.40 (0.60-3.27)	0.84 (0.40-1.76)
Quartile 4	2.24 (1.05-4.79)	3.03 (1.25-7.34)	2.86 (1.20-6.81)	1.76 (0.87-3.56)
ROC AUC	0.784	0.846	0.820
Model 3*
Lowest Quartile	1.00	1.00	1.00	1.00
Quartile 2	2.60 (1.10-6.12)	1.23 (0.46-3.29)	0.84 (0.30-2.38)	0.86 (0.40-1.89)
Quartile 3	1.23 (0.50-3.06)	0.88 (0.32-2.40)	1.04 (0.40-2.72)	0.56 (0.24-1.31)
Quartile 4	2.95 (1.33-6.52)	3.10 (1.17-8.24)	3.03 (1.21-7.62)	2.40 (1.10-5.22)
ROC AUC	0.788	0.859	0.836

^*Models are as specified in Table 2.