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. 2014 Feb 14;5:26. doi: 10.3389/fgene.2014.00026

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Copyright © 2014 Quinlan, Idaghdour, Goulet, Gbeha, de Malliard, Bruat, Grenier, Gomez, Sanni, Rahimy and Awadalla.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Examples of significant SNP-by-clinical status interaction effects. Five SNP-by-clinical status interaction effects are shown. All are local eSNP interactions. Expression levels are shown on the y-axis, and SNP genotype on the x-axis. The eSNP interaction involving gene zinc finger and SCAN domain containing 12 pseudogene 1 (ZSCAN12L1) is shown in (A); chromosome 9 open reading frame 173 (C9ORF173) is shown in (B); capping protein (actin filament) muscle Z-line, alpha 1 (CAPZA1) is shown in (C); supervillin (SVIL) is shown in (D); and myocyte enhancer factor 2A (MEF2A) is shown in (E). Linear regression for each group is plotted and colored: yellow for follow-up, FU; purple for entry, E; and red for controls, Ctls. See also Figure S7.