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The redox status of XRCC1 protein in Xrcc1+/+ cells after various cell treatments as indicated. Measurements were by mass spectrometry as described in detail in Section 2. Relative amounts of the C12-C20 unmodified (oxidized) and carbamidomethylated (reduced) forms of the native XRCC1 peptides were calculated using the ratios of the natural abundance areas to the areas from the appropriate non-modified and carbamidomethylated synthetic peptides.
