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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: DNA Repair (Amst). 2013 Jul 18;12(9):774–785. doi: 10.1016/j.dnarep.2013.06.004

Table 2. Fold 4-AN-mediated sensitization to MMS*.

MMS IC50 (mM) Fold
Cell line − 4-AN + 4-AN sensitization
Xrcc1+/+ 1.5 0.06 22
XV2 0.6 0.05 12
XRE8 1.1 0.2 5
Xrcc1−/− 0.2 0.02 13
*

1 h exposure to MMS, 24 h exposure to 4-AN (5 μM)