Table 1. Reports of clinical studies of comparison between TACE plus HIFU and TACE alone (reported in English).
Author/Country | Year | Treatment | No. of patients | Tumor size | PVTT (yes) | ORR | OS rate (%) |
|
---|---|---|---|---|---|---|---|---|
1 year | 3 years | |||||||
Feng et al. (13)/China | 2005 | TACE plus HIFU | 24 | 10.0 cm (mean) | 33% | 21 (87.5%)# | 42.9# | NA |
TACE | 26 | 11.3 cm (mean) | 50% | 11 (42.3%) | 0 | NA | ||
Li et al. (16)/China | 2010 | TACE plus HIFU | 44 | NA | NA | 72.8%# | 72.7# | 50.0# |
TACE | 45 | NA | NA | 44.5% | 47.2 | 2.8 | ||
Lin et al. (17)/China | 2012 | TACE plus PVE plus HIFU | 32 | 5.1-12.3 cm (range) | 40.6% | 25.0% | 56.3# | 9.3# |
TACE plus PVE | 36 | 4.0-15.3 cm (range) | 38.9% | 8.3% | 30.6 | 0 |
TACE, transcatheter arterial chemoembolization; HIFU, high-intensity focused ultrasound ablation; PVTT, portal vein tumor thrombus; ORR, objective response rate; PVE, portal vein embolization; OS, overall survival; #, statistically significant; NA, not available