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. 2013 Jun;2(3):168–170. doi: 10.3978/j.issn.2304-3881.2013.03.01

Table 1. Reports of clinical studies of comparison between TACE plus HIFU and TACE alone (reported in English).

Author/Country Year Treatment No. of patients Tumor size PVTT (yes) ORR OS rate (%)
1 year 3 years
Feng et al. (13)/China 2005 TACE plus HIFU 24 10.0 cm (mean) 33% 21 (87.5%)#     42.9#     NA
TACE 26 11.3 cm (mean) 50% 11 (42.3%)     0     NA
Li et al. (16)/China 2010 TACE plus HIFU 44 NA NA 72.8%#     72.7#     50.0#
TACE 45 NA NA 44.5%     47.2     2.8
Lin et al. (17)/China 2012 TACE plus PVE plus HIFU 32 5.1-12.3 cm (range) 40.6% 25.0%     56.3#     9.3#
TACE plus PVE 36 4.0-15.3 cm (range) 38.9% 8.3%     30.6     0

TACE, transcatheter arterial chemoembolization; HIFU, high-intensity focused ultrasound ablation; PVTT, portal vein tumor thrombus; ORR, objective response rate; PVE, portal vein embolization; OS, overall survival; #, statistically significant; NA, not available