Figure 6.

Differential expression after MLL-AF9 knockdown of genes considered as likely mediators of MLL-AF9 leukemogenic effects. Columns show log₂FC from microarray data of MLL-AF9 knockdown versus control treatments on day 8. Standard error of the mean is indicated. Transcripts are sorted according to categories of encoded proteins and alphabetically. Dotted division lines indicate proteins assorted to two categories. *Genes coding for proteins which belong to conventionally druggable protein classes as described by Rask-Andersen et al. [11].