Table 2.
Thrombolysis proportions, sICH, thrombolysis times and 30-day case fatality from 2005 to 2011 in Joinville, Brazil
| 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | All | |
|---|---|---|---|---|---|---|---|---|
| IS, n | 526 | 469 | 402 | 498a | 524 | 596 | 537 | 3,552 |
| IS lysed, n | 7 | 18 | 22 | 54 | 31 | 37 | 51 | 220 |
| IS lysed (95% CI), % | 1.3 (0.5 – 2.7) | 3.8 (2.3 – 6.6) | 5.5 (3.5 – 8.2) | 10.8 (8.3 – 13.9) | 5.9 (4.1 – 8.3) | 6.1 (4.2 – 8.5) | 11.2 (8.6 – 14.2) | 6.2 (5.4 – 7.0) |
| 7-day ICH after lysis, % (n) | 0 | 0 | 9.1 (2/22) | 9.3 (5/54) | 6.5 (2/31) | 10.8 (4/37) | 1.7 (1/60) | 6.4 (14/220) |
| Death with sICH, % (n) | 0 | 100 (1/1) | 50 (1/2) | 40 (2/5) | 100 (2/2) | 25 (1/4) | 100 (1/1) | 57 (8/14) |
| Median thrombolysis time (IQR), min | ||||||||
| Symptom-to-door | 86 (33 – 129) | 101 (66 – 118) | 60 (37 – 96) | 117 (97 – 131) | 96 (71 – 122) | 60 (38 – 85) | 91 (60 – 128) | 71 (51 – 113) |
| Door-to-needle | 67 (54– 127) | 50 (27 – 69) | 64 (50 – 112) | 83 (68 – 108) | 74 (59 – 89) | 83 (68 – 108) | 80 (54 – 120) | 79 (53 – 115) |
| Lysed within 1 h after | ||||||||
| hospital arrivala, % (n) | 28.6 (2/7) | 16.6 (3/18) | 30.9 (9/22) | 45 (19/42) | 24 (7/29) | 15.6 (5/32) | 33.4 (5/15) | 30.3 (50/165) |
| 30-day case fatality, % (n) | 29 (2/7) | 28 (5/18) | 14 (3/22) | 31 (17/54) | 42 (13/31) | 32 (12/37) | 32 (16/51) | 29 (64/220) |
a
Data available in 75% (165/220).