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. 2013 Dec 20;3(1):156–166. doi: 10.1159/000356984

Table 3.

Functional outcome after 12 months between first-ever IS thrombolyzed in 4.5 h and not throm-bolyzed in Joinville, 2009 – 2011

No lysis (n = 544) Lysis (n = 107) p
Demographic data
  • Mean age ± SD, years

69.3 ± 14.0 68.8± 13.3 0.608
  • Females

290 (53.3) 50 (46.7) 0.244
  • Age strata

  •  ≤54 years

87 (16.0) 14 (13.1) 0.460
  •  55 – 74 years

240 (44.1) 54 (50.5)
  •  >75 years

217 (39.9) 39 (36.4)
NIH scale
  • Median NIH (IQR)

12 (7 – 22) 12 (9 – 20) 0.731
  • NIH categories

<0.001
  •  4 – 8 (mild)

194 (35.7) 25 (23.4)
  •  9 – 13 (moderate)

109 (20.0) 32 (29.9)
  •  14 – 22 (severe)

108 (19.9) 37 (34.6)
  •  >22 (coma)

133 (24.4) 13 (12.1)
CV risk factors
 Hypertension 441 (81.1)a 73 (68.2)b 0.012
 Diabetes 199 (36.6)c 25 (23.4) 0.027
 Smoking 105 (19.3) 16 (15.0) 0.409
 yocardial infarction 62 (11.4)d 11 (10.3)e 0.878
 Atrial fibrillation 77 (14.2)f 17 (15.9)g 0.134
TOAST classification 0.033
 Atherothrombotic 122 (22.4) 23 (21.5)h
 Lacunar 70 (12.9) 9 (8.4)
 Cardioembolic 199 (36.6) 39 (36.4)
 Undetermined 101 (18.6) 22 (20.6)
 Other 52 (9.6) 12 (11.2)
Bamford classification 0.064
 LACS 78 (14.3)i 7 (6.5)
 PACS 239 (43.9) 56 (52.3)
 TACS 188 (34.6) 41 (38.3)
 POCS 32 (5.9) 3 (2.8)
Years of education <0.001
 Unknown 7 (1.3) 15 (14.0)
 Illiterate (<4 years) 223 (41.0) 33 (30.8)
 4 years 212 (39.0) 41 (38.3)
 8 years 39 (7.2) 6 (5.6)
 11 years 46 (8.5) 11 (10.3)
>11 years 17 (3.1) 1 (0.9)
mRS at 12 months 0.116
 0 41 (7.5) 13 (12.1)
 1 90 (16.5) 25 (23.4)
 2 41 (7.5) 4 (3.7)
 3 48 (8.8) 7 (6.5)
 4 65 (11.9) 7 (6.5)
 5 19 (3.5) 2 (1.8)
 6 240 (44.1) 49 (45.8)
 0 – 1 131 (24.1) 38 (35.5) 0.016
 0 – 2 172 (31.6) 42 (39.3) 0.143
 3 – 5 132 (24.3) 16 (15.0) 0.043
 3 – 6 372 (68.4) 65 (60.7) 0.143
a

Data are number (%), unless otherwise indicated. CV = Cardiovascular; LACS = lacunar syndrome; PACS = partial anterior circulation syndrome; TACS = total anterior circulation syndrome; POCS = posterior circulation syndrome. Unavailable: hypertension 3 cases

b

1 case

c

diabetes 1 case

d

myocardial infarction 19 cases

e

3 cases

f

atrial fibrillation 29 cases

g

1 case

h

TOAST 2 cases

i

Bamford 7 cases.