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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Leukemia. 2013 Sep 5;28(2):398–403. doi: 10.1038/leu.2013.258

Table 2.

Relationship between Non-overlapping primary molecular cytogenetic abnormalities and myeloma defining event at diagnosis in patients with immunoglobulin heavy chain (IgH) translocations.

FISH Abnormality No. Of patiets Bone Disease variant Renal Failure variant Anemia Variant Mixed Variant
t(11;14), No. of patients (%) 86 30 (34.9%) 6 (7.0%) 12 (14.0%) 38 (44.2%)
t(4;14), No. of patients (%) 47 12 (25.5%) 3 (6.4%) 11 (23.4%) 21 (44.7%)
t(14;16), No. of patients (%) 24 3 (12.5%) 6 (25.0%) 4 (4.2%) 11 (45.8%)
t(14;20), No. of patients (%) 1 0 (0%) 0 (0%) 0 (0%) 1 (1.0%)
t(6;14), No. of patients (%) 3 1 (33.3%) 0 (0%) 1 (33.3%) 1 (33.3%)
Unknown Partner/Deletion of IgH Region, No. of patients (%) 59 22 (37.3%) 8 (13.6%) 5 (8.5%) 24 (40.7%)
*

Number and proportion represents the breakdown of patients with each cytogenetic subtype according to MDE