Table 2.
Treatment-related AEs
| Adverse event | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | Total affected n (%) |
|---|---|---|---|---|---|---|
| Worst grade per patient: severe events, n | ||||||
| Lymphopenia | 2 | 2 | 5 | 2 | 0 | 11 (85) |
| Anemia | 2 | 0 | 1 | 0 | 0 | 3 (23) |
| Increased INR | 0 | 1 | 1 | 0 | 0 | 2 (15) |
| Acute coronary syndrome | 0 | 0 | 1 | 0 | 0 | 1 (8) |
| Gastric hemorrhage | 0 | 0 | 0 | 0 | 1 | 1 (8) |
| Gastric ulcer | 0 | 0 | 1 | 0 | 0 | 1 (8) |
| Hyponatremia | 0 | 0 | 1 | 0 | 0 | 1 (8) |
| Worst grade per patient: mild and moderate events, n | ||||||
| Nausea or vomiting | 6 | 1 | 0 | 0 | 0 | 7 (54) |
| Fatigue | 4 | 2 | 0 | 0 | 0 | 6 (46) |
| Thrombocytopenia | 4 | 1 | 0 | 0 | 0 | 5 (38) |
| Anorexia | 2 | 0 | 0 | 0 | 0 | 2 (15) |
| Chills | 2 | 0 | 0 | 0 | 0 | 2 (15) |
| Leukopenia | 1 | 1 | 0 | 0 | 0 | 2 (15) |
| Oral mucositis | 1 | 1 | 0 | 0 | 0 | 2 (15) |
| Diarrhea | 0 | 1 | 0 | 0 | 0 | 1 (8) |
| Dry skin | 1 | 0 | 0 | 0 | 0 | 1 (8) |
| Hand-foot syndrome | 0 | 1 | 0 | 0 | 0 | 1 (8) |
| Hypoalbuminemia | 1 | 0 | 0 | 0 | 0 | 1 (8) |
| Hypocalcemia | 1 | 0 | 0 | 0 | 0 | 1 (8) |
| Hypomagnesemia | 1 | 0 | 0 | 0 | 0 | 1 (8) |
| Skin ulceration | 1 | 0 | 0 | 0 | 0 | 1 (8) |
| Transaminase elevation | 1 | 0 | 0 | 0 | 0 | 1 (8) |
All events considered to be at least possibly related to treatment are shown.