Table 1. Rat lung tissue adenine nucleotide content (μmol·gram−1 dry lung) after 15 min of perfusion with the experimental treatments in Protocol 1 studies.
Treatment | n | ATP | ADP | AMP |
ATP + ADP + AMP |
---|---|---|---|---|---|
Vehicle Control | 7 | 5.66 ± 0.46 b | 1.17 ± 0.14 b,c | 0.31 ± 0.06 c | 7.15 ± 0.33 b |
Rotenone | 8 | 2.34 ± 0.15 c | 1.83 ± 0.09 a | 1.73 ± 0.29 b | 5.90 ± 0.37 c |
Rotenone + CoQ1 | 7 | 5.38 ± 0.29 b | 1.22 ± 0.07 b | 0.30 ± 0.04 c | 6.90 ± 0.35 b,c |
CoQ1 | 4 | 7.72 ± 0.36 a | 0.93 ± 0.05 c | 0.14 ± 0.04 d | 8.79 ± 0.34 a |
Rotenone + CoQ1 + Dicumarol | 5 | 1.23 ± 0.09 e | 1.58 ± 0.04 a | 3.12 ± 0.22 a | 5.93 ± 0.35 c |
Rotenone + CoQ1 + Antimycin A |
5 | 1.68 ± 0.05 d | 1.58 ± 0.04 a | 2.84 ± 0.30 a | 6.10 ± 0.23 c |