Table 2. Lung lactate and pyruvate production over the 15 min treatment periods (μmol ·15 min−1·gram−1 dry lung) in Protocol 1 studies.
Treatment | n | Lactate | Pyruvate |
Lactate + Pyruvate |
---|---|---|---|---|
Vehicle Control | 4 | 12.36 ± 1.64 c | 0.88 ± 0.11 d | 13.24 ± 1.66 c |
Rotenone | 4 | 38.62 ± 3.14 a | 0.87 ± 0.14 d | 39.49 ± 3.12 a |
Rotenone + CoQ1 | 3 | 24.64 ± 1.96 b | 2.58 ± 0.20 a | 27.23 ± 1.92 b |
CoQ1 | 4 | 14.77 ± 2.02 c | 2.12 ± 0.18 a,b | 16.90 ± 2.08 c |
Rotenone + CoQ1 + Dicumarol | 4 | 34.31 ± 0.81 a | 1.70 ± 0.26 b,c | 36.01 ± 0.97 a |
Rotenone + CoQ1 + Antimycin A |
4 | 34.63 ± 2.22 a | 1.42 ± 0.06 c | 36.05 ± 2.19 a |