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eVLP induction of IFNβ and ISGs requires TRIF. BMDCs generated from TRIF+/+ and TRIF−/− mice were stimulated with eVLP for 6 h, and mRNA transcript of indicated cytokines was measured as described previously. TRIF-dependent and TRIF-independent cytokines are shown in this figure and in Table 2, respectively. Data represent the mean of duplicate samples from 3 independent experiments ±SEM. All data were assessed by Student's t test and are denoted by **P≤0.01 and *P≤0.05.
