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eVLP induction of ISGs depends on IFNAR-mediated type I IFN signaling. BMDCs generated from type I IFN receptor1 (IFNAR1+/+ and IFNAR1−/−) mice (both BALB/C background) were stimulated with eVLP for 6 h, and the expression of specified cytokines were measured as in Fig. 1. Data represent the mean of duplicate samples from 3 independent experiments ±SEM. All data were assessed by Student's t test and are denoted by **P≤0.01, *P≤0.05 and n.s., no significance.
