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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: J Affect Disord. 2013 Nov 16;155:247–254. doi: 10.1016/j.jad.2013.08.041

Figure 4.

Figure 4

Effects of AMPT on exploratory behavior in male C57BL6/J mice in the BPM. The tyrosine hydroxylase inhibitor AMPT (10, 30, and 100 mg/kg) was administered to mice at 24, 20, and 4 h prior to their assessment in the BPM. AMPT at the highest dose reduced activity as measured by reduced transitions (a), but not center entries (b). AMPT at the highest dose reduced exploratory behavior as measured by a non-significant drop in rearing (c) and a significant drop in holepoking (d). AMPT did not affect spatial d (e), but reduced entropy at the highest dose (f). Data are presented as mean + S.E.M. * p<0.05 and # p<0.1 when compared to saline; ! p<0.05 and $ p<0.1 when compared to AMPT 10 mg/kg.