Table 4.
Enriched biological pathways assigned to vWF, HA, and AF by PHPN
|
Von Willebrand factor/ |
Atrial fibrillation (AF) pathways
1
|
Hippocampal atrophy (HA)
1
|
|||
|---|---|---|---|---|---|
| factor VIII pathways 1 | pathways | ||||
| [5412] |
Arrhythmogenic right ventricular |
[1100]
|
Metabolic pathways
|
[4360] |
Axon guidance |
| [4662] |
B cell receptor signaling pathway |
[670] |
One carbon pool by folate |
[4623] |
Cytosolic DNA-sensing pathway |
| [4514] |
Cell adhesion molecules (CAMs) |
|
|
[531] |
Glycosaminoglycan degradation |
| [4062] |
Chemokine signaling pathway |
|
|
[4142] |
Lysosome |
| [4664] |
Fc epsilon RI signaling pathway |
|
|
[1100]
|
Metabolic pathways
|
|
[1100]
|
Metabolic pathways
|
|
|
[510] |
N-Glycan biosynthesis |
| [4666] |
Fc gamma R-mediated phagocytosis |
|
|
[4151] |
PI3K-Akt signaling pathway |
| [4510] |
Focal adhesion |
|
|
[4141] |
Protein processing in endoplasmic reticulum |
| [4670] |
Leukocyte trans endothelial migration |
|
|
[4530] |
Tight junction |
| [4650] |
Natural killer cell mediated cytotoxicity |
|
|
|
|
| [4810] |
Regulation of actin cytoskeleton |
|
|
|
|
| [4660] |
T cell receptor signaling pathway |
|
|
|
|
| [4742] | Taste transduction | ||||
1Pathways listed are identified enriched pathways for indicated phenotypes; numbers in square brackets indicate the Kyoto Encyclopedia of Genes and Genomes (KEGG) identifiers for specified pathways.
2Common biological pathway is indicated in bold.