Effects of ADN-1184 in tests of motor interference. (A) Catalepsy induced by ADN-1184. Each symbol represents mean ± SEM, catalepsy was measured 30, 60 and 120 min after drug administration (n = 8 per group). **P < 0.01, compared with vehicle-injected control group using Mann–Whitney U-test, following significant Kruskal–Wallis anova. (B) Effects of ADN-1184 on spontaneous locomotor activity. Distance travelled by rats was recorded 61–90 min after substance injection (n = 8 per group). **P < 0.01, compared with vehicle-injected control group using Newman–Keuls post hoc test, following significant anova.