Table 2.

Mean pharmacokinetic parameters following i.v bolus (1 mg kg⁻¹ over 5 min) of ADX71441 in three male guinea pigs (G1–3)

	G1	G2	G3	Mean	SD
C0 (ng mL−1)	367	366	293	342	34.6
t1/2 (h)	2.57	3.11	2.88	2.85	0.3
Vdds (L kg−1)	6.6	7.5	7.0	7.0	0.5
Cl (mL min−1 kg−1)	35.7	34.3	33.5	34.5	1.1