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. 2014 Jan 24;171(4):1054–1067. doi: 10.1111/bph.12534

Table 1.

Activation and steady-state inactivation properties of Na+ currents carried by NaV1.1, NaV1.2, NaV1.3 and NaV1.6 α-subunits

Activation Inactivation
Subtype Vh (mV) Vc (mV) Gmax (nS) Vh (mV) Vc (mV) ΔVh (mV)
NaV1.1 (n = 34) −27.1 ± 0.8aa,bb 5.4 ± 0.2aa,bb 74.1 ± 4.2aa,bb −59.4 ± 0.9aa −5.5 ± 0.3aa 32.4 ± 1.0aa,bb,cc
NaV1.2 (n = 34) −24.3 ± 1.0aa 4.7 ± 0.2aa,cc 76.1 ± 4.4cc,dd −60.5 ± 0.8bb −4.9 ± 0.1aa,bb,cc 36.2 ± 0.9a,aa
NaV1.3 (n = 30) −23.0 ± 0.7bb,cc 4.6 ± 0.2bb,dd 98.4 ± 5.5aa,cc,ee −58.6 ± 0.5cc −5.9 ± 0.1bb 35.6 ± 0.7b,bb
NaV1.6 (n = 37) −25.9 ± 0.4cc 5.6 ± 0.1cc,dd2002 55.8 ± 2.7bb,dd,ee2002 −64.3 ± 0.5aa,bb,cc −5.7 ± 0.1cc 38.4 ± 0.5a,b,cc

ΔVh indicates the difference between the activation Vh and inactivation Vh values. Cell numbers are given in brackets.

a b

P < 0.05.

aa bb cc dd ee

P < 0.01; ANOVA, followed by Fisher's LSD post hoc test.