Table 1.
Activation | Inactivation | |||||
---|---|---|---|---|---|---|
Subtype | Vh (mV) Vc (mV) Gmax (nS) | Vh (mV) Vc (mV) | ΔVh (mV) | |||
NaV1.1 (n = 34) | −27.1 ± 0.8aa,bb | 5.4 ± 0.2aa,bb | 74.1 ± 4.2aa,bb | −59.4 ± 0.9aa | −5.5 ± 0.3aa | 32.4 ± 1.0aa,bb,cc |
NaV1.2 (n = 34) | −24.3 ± 1.0aa | 4.7 ± 0.2aa,cc | 76.1 ± 4.4cc,dd | −60.5 ± 0.8bb | −4.9 ± 0.1aa,bb,cc | 36.2 ± 0.9a,aa |
NaV1.3 (n = 30) | −23.0 ± 0.7bb,cc | 4.6 ± 0.2bb,dd | 98.4 ± 5.5aa,cc,ee | −58.6 ± 0.5cc | −5.9 ± 0.1bb | 35.6 ± 0.7b,bb |
NaV1.6 (n = 37) | −25.9 ± 0.4cc | 5.6 ± 0.1cc,dd2002 | 55.8 ± 2.7bb,dd,ee2002 | −64.3 ± 0.5aa,bb,cc | −5.7 ± 0.1cc | 38.4 ± 0.5a,b,cc |
ΔVh indicates the difference between the activation Vh and inactivation Vh values. Cell numbers are given in brackets.
P < 0.05.
P < 0.01; ANOVA, followed by Fisher's LSD post hoc test.