Table 1. Renal function, renal and systemic hemodynamics in control (C), Bothrops venom (BV), Schizolobium parahyba aqueous extract (SP) and BV followed by SP (T) groups.

	C	BV	SP	T
GFR (ml/min/100g)	0.88±0.13	0.47±0.15 a	0.64±0.12 b	0.52±0.22 a
	(8)	(8)	(8)	(8)
RBF (ml/min)	6.4 (6.0–7.1)	3.0 (2.3–3.5)a , c	6.3 (6.0–6.9)	3.7 (3.0–4.8)a , d
	(10)	(10)	(10)	(10)
RVR (mmHg/ml/min)	20 (17–25)	39 (31–60)a , c	21 (18–24)	34 (23–40)e , f
	(10)	(10)	(10)	(10)
MAP (mmHg)	135±16	128±23	133±13	120±14
	(10)	(10)	(10)	(10)
UO (µl/min)	182±90	203±152	168±88	177±94
	(8)	(8)	(8)	(8)
FeNa (%)	0.4 (0.1–1.0)	1.4 (0.5–3.0)	0.3 (0.2–1.0)	0.8 (0.4–2.3)
	(10)	(9)	(9)	(9)
FeK (%)	23±13	36±19	20±9	28±9
	(10)	(9)	(9)	(9)
Uosm (mOsm/kg)	1,305 (1,019–1,496)	569 (530–744)b , e	1,275 (945–1,504)	669 (468–772)b , e
	(10)	(9)	(10)	(10)

Data are mean ± SD or median (quartiles); (n); GFR: glomerular filtration rate; RBF: renal blood flow; RVR: renal vascular resistance; MAP: mean arterial pressure; UO: urinary output; FeNa: fractional excretion of sodium; FeK: fractional excretion of potassium; Uosm: urinary osmolality.

^ap<0.001 vs. control;

^bp<0.01 vs. control;

^cp<0.001 vs. SP;

^dp<0.01 vs. SP;

^ep<0.05 vs. control;

^fp<0.05 vs. SP.