Table 6. Summary of study outcomes – Iron Treatment vs. Malaria Risk.
Author, Year | Study Design | Outcome | Exposure% (n) | Comparison to exposure% (n) | Risk estimate (95% CI)or p-value |
Oppenheimer, 1986 [63] | Retrospective Cohort | Postnatal malaria- primigravida | Total Dose Iron Infusion 20·4% (11/54) | No Total Dose Iron Infusion 4·5% (3/67) | RR 4·55 (1·34–15·49) OR 5·46 (1·44, 20·7) |
Postnatal malaria- multigravida | Total Dose Iron Infusion 8·4% (8/95) | No Total Dose Iron Infusion 7·6% (14/184) | RR 1·11 (0·48–2·54) OR 1·12 (0·45, 2·76) | ||
Byles, 1970 [62] | Prospective Cohort | Generalized reactions after total dose iron infusion | Total dose iron+Concurrent CQ 1·5% (7/462) | Total dose iron+No concurrent CQ 8·6% (39/455) | OR 0·16 (0·07–0·37) RR 0·18 (0·08–0·39) |
PF parasitemia present among participants with generalized reactions after total dose iron infusion | Total dose iron+Concurrent CQ 0·0% (0/7) | Total dose iron+No concurrent CQ 28·2% (11/39) | p = 0·17 |
CI: confidence interval. CQ: chloroquine. OR: odds ratio. PF: Plasmodium falciparum. RR: risk ratio.