Table 1.
Demographic features
| Subjects with APS (N = 30) | Subjects with aPL (N = 72) | |
|---|---|---|
| Gender | ||
| Male | 3 (10.0%) | 11 (15.3%) |
| Female | 27 (90.0%) | 61 (84.7%) |
| Ethnic group* | ||
| Caucasian | 22 (73.3%) | 50 (69.4%) |
| Afro-American | 5 (16.7%) | 13 (18.1%) |
| Hispanic | 2 (6.7%) | 4 (5.6%) |
| Others | 1 (3.3%) | 4 (5.6%) |
| Mean age | 46.7 (± 12.0) | 47.7 (± 12.0) |
| Primary APS/aPL | 11 (33.3%) | 19 (26.4%) |
| APS/aPL secondary to SLE | 19 (63.3%) | 53 (73.6%) |
| Elevated IgG (aCL) | 12 (40.0%) | 21 (29.2%) |
| Elevated IgM (aCL) | 5 (16.7%) | 22 (30.6%) |
| Positive LAC | 18 (60.0%) | 46 (63.9%) |
| Median IgG | 42 ± 5.5 – 69.5 | 15.8 ± 4.4 – 73.9 |
| Median IgM | 21.8 ± 4.1 – 64.9 | 24.5 ± 5.4 – 66.5 |
APS = antiphospholipid antibody syndrome
aPL = antiphospholipid antibodies
SLE = systemic lupus erythematosus
aCL = anticardiolipin antibodies
LAC = lupus anticoagulant
Ethnicity of 1 subject with aPL is unknown.
4 subjects with symptomatic APS and 6 subjects with asymptomatic APS had more than one elevated or positive marker.
In the subjects with symptomatic APS: 7 subjects had missing aCL values. 1 subject had only one value of IgG. 3 subjects had only one value of IgM. 3 subjects had only one value of both IgG and IgM. 4 subjects had only one value of LAC.
In the subjects with asymptomatic APS: 2 subjects had missing aCL values. 1 subject had missing LAC values. 1 subject had only one value of IgM. 4 subjects had only one value of LAC.