Table 1. Summary of the status of animals and tissue analysis.
Group name (total numberof animals) | Description | Number of animals in analysis | ||
Biochemistry(& behavior) | IHC(& behavior) | HPLC | ||
Intact (N = 13) | non-operated | 5 (3) | 4 | 4 |
Spinal (N = 4) | transected | – | – | 4 |
SP-PBS (N = 8) | transected and bilaterally injected with PBS | 3 (3) | 5 | – |
SP-EGFP (N = 4) | transected and bilaterally injected with AAV1/2-SYN-EGFP | – | 4 | – |
SP-BDNF (N = 11*) | transected and bilaterally injected with AAV1/2-SYN-BDNF | 4 (4) | 5 (7*) | – |
*Two animals from this group had died before the end of the experiment and thus were tested only behaviorally in the early post-operative period (see text for details).
Numbers in brackets mark those animals which were used for both behavioral and biochemical analyses.