Figure 1.
Pedigree of the studied family. For clarity purpose, the numbering of the individuals in the present pedigree were kept identical to the initial description of Pettigrew et al,3 with individuals 2b, 3b and 7b being individuals 2, 3 and 7 in Pettrigew et al.3 An affected male born in the interval was added in generation V. Individuals for whom a DNA sample is available are represented with a dash above their symbol. Hatched symbols represent clinically affected individuals for whom a DNA sample was not available to perform molecular screening. Obligate carrier females are indicated.