Table 1.
Clinical characteristics of the sepsis patients (n = 32)
| Parameters | Septic shock (n = 10) | Gram-positive (n = 10) | Gram-negative (n = 12) | Healthy controls (n = 13) |
|---|---|---|---|---|
| Age, median years (range) | 74 (51–87) | 68.5 (33–89) | 51 (20–79) | 46 (26–64) |
| Males | 7 | 7 | 4 | 4 |
| 28-day mortality | 3 | 1 | ||
| Length of ICU stay | ||||
| Days median (range) | 6 (1–49) | 0 | 0 | n/a |
| Length of hospitalization | ||||
| Days median (range) | 23 (3–53) | 7 (3–55) | 4 (3–46) | n/a |
| Ventilation | ||||
| Days median (range) | 6 (0–49) | 0 | 0 | n/a |
| Nosocomial infection | ||||
| Percentage (number) | 50 (n = 5) | 0 | 0 | n/a |
| WBC count at enrollment | ||||
| Cells (×106)/ml median (range) | 20 (1.5–60.4) | 18 (8.6–32.3) | 8.7 (5.1–32.4) | 5.7 (4.6–11) |
| Lymphocyte count at enrollment | ||||
| Cells (×106)/ml median (range) | 1 (0.1–2.4) | 1 (0.3–2.1) | 1.2 (0.5–2.4) | 1.8 (0.8–3.7) |
| Comorbidities | ||||
| Diabetes | 3 | 3 | 3 | n/a |
| Renal failure | 1 | 1 | 0 | n/a |
| Cardiovascular disease | 5 | 6 | 4 | n/a |
| Pulmonary disease | 6 | 3 | 0 | n/a |
| Metastatic cancer | 1 | 0 | 1 | n/a |
| Blood or urine culture finding | ||||
| Escherichia coli | 4 | n/a | 10 | n/a |
| Citrobacter koseri | 0 | n/a | 1 | n/a |
| Staphylococcus aureus (1 TSSS+) | 2 | 3 | n/a | n/a |
| Streptococcus pyogenes | 1 | 0 | n/a | n/a |
| Klebsiella oxytoca | 1 | n/a | 0 | n/a |
| Klebsiella pneumoniae | 0 | n/a | 1 | n/a |
| Streptococcus pneumoniae | 0 | 4 | n/a | n/a |
| Gram-positive anaerobic cocci | 0 | 1 | n/a | n/a |
| No bacteria isolated from blood/urine | 2 | 2 | 0 | n/a |