Skip to main content
. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Clin Perinatol. 2013 Dec 12;41(1):47–67. doi: 10.1016/j.clp.2013.09.007

Figure 3. Germinal matrix vasculature is deficient in fibronectin and lack GFAP+ astrocyte endfeet coverage.

Figure 3

A) Representative immunofluorescence of cryosection from germinal matrix and white matter of a 24 week premature human infant labeled with fibronectin (red) specific antibody. Fibronectin is strongly expressed in the white matter whereas it is weakly expressed in the germinal matrix (arrowheads). Scale bar; 20μm. B) Cryosection from germinal matrix and white matter of a 24 week premature infant was double-labeled with CD34 (endothelium, red) and GFAP (astrocyte, green) specific antibody. GFAP positive astrocyte endfeet are intimately associated with the outer endothelial surface in the white matter (arrowheads). However, GFAP positive astrocytes are not covering endothelium in the germinal matrix (arrows).