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. Author manuscript; available in PMC: 2014 Dec 12.
Published in final edited form as: J Med Chem. 2013 Nov 21;56(23):9471–9481. doi: 10.1021/jm400794z

Figure 3.

Figure 3

a) Fluorescence titrations of TAMRA-(CUG)6 with ligands. Comparison of normalized fluorescence intensity change of TAMRA-(CUG)6 in the presence of increasing concentrations of ligands. TAMRA was excited at 560 nm and its emission was recorded at 590 nm. Error bars represent mean ± s.d. of three independent experiments. b) KD was derived by fitting the Fluorescence intensities at different concentrations of ligands into the following equation: F=Fmax−F01+(KD[L])n+F0 where [L] is the concentration of each ligand and Fmax and F0 are the maximum and minimum of normalized fluorescence intensities, respectively.