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. Author manuscript; available in PMC: 2014 Dec 12.

Published in final edited form as: J Med Chem. 2013 Nov 21;56(23):9471–9481. doi: 10.1021/jm400794z

Confocal fluorescent images show CUG^exp foci in DM1 model cells are present in rows 2-6, no ligand treatment, treated with spermine (negative control), 2, 9 and 5, respectively. CUG^exp foci are not present in negative control cells, row 1, as well as row 7 where DM1 cell model is treated with 9, for 36 h. Corresponding fluorophores in columns 1-3 are TO-PRO-3, Acridine ring and Cy3-(CAG)₁₀ FISH probe, respectively.

Confocal fluorescent images show CUG^exp foci in DM1 model cells are present in rows 2-6, no ligand treatment, treated with spermine (negative control), 2, 9 and 5, respectively. CUG^exp foci are not present in negative control cells, row 1, as well as row 7 where DM1 cell model is treated with 9, for 36 h. Corresponding fluorophores in columns 1-3 are TO-PRO-3, Acridine ring and Cy3-(CAG)₁₀ FISH probe, respectively.